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United Kingdom The Pearl-Rose Clinic (Hypertension & Cardiovascular Risk), Hammersmith Hospital, London Dr. Chapman, Neilneil.chapman1@nhs.net William Harvey Research Institute, Department of Clinical Pharmacology, Queen Mary and Wesfield College, St Bartholomew's Royal London School of Medicine & Dentistry, London Dr. Kapil, Vikasv.kapil@qmul.ac.uk